ImmaturemonocytesacquireantigensfromothercellsinthebonemarrowandpresentthemtoTcellsaftermaturingintheperiphery
...renotrecognizedtodirectlyparticipateinantigenpresentation.Wedevelopedtechniquestolabelmousemonocytesubsetswithparticulatetracersinvivo.Gr-1lobutnotGr-1himonocyteswerestablylabeledbyintravenousinjectionof0.5-μmmicrospheres.Gr-1himonocytescouldbelabeledwhenthemicrosphereswereinjectedaftersystemicdepl...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第3期InsulintreatmentenhancesAT1receptorfunctioninOKcells
...fectsofANGIIontheactivitiesofNKAandNHEweremeasuredintheintactcells,whilethequantificationofAT1receptorexpressionwasperformedinthecellmembranesandthecellextracts,asdescribedbelow.QuantificationofAT1receptors.OKcellmembraneswereprepared,aswedescribedearlier(27).Briefly,OKcellswerelysedwith10mMtris[hyd...
醫源資料庫;在線期刊;美國生理學雜誌;2005年第288卷第6期CompleteFcRndependenceforintravenousIgtherapyinautoimmuneskinblisteringdiseases
...ferredtoasBPAg1)isanintracellularproteinthatlocalizestothehemidesmosomalplaque(2,3).Incontrast,BP180(alsoreferredtoasBPAG2ortypeXVIIcollagen)isatransmembraneprotein(4,5).TheextracellularregionofBP180consistsof15collagendomainsseparatedfromoneanotherbynon-collagensequences.BP180-specificautoantibodie...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第12期滷米松乳膏與祛白酊聯合外用治療白癜風
...松祛白酊白癜風 ObservationontheeffectofhalometasoneointmentandQu-baitinctureonvitiligo. LIANGXiong-an,DENGBIN,TANGShu-kun. (DepartmentofDermatology,TheAffiliatedHospitalofHainanMedicalCollege,Haikou570102,Hainan,P.R.China)0.05),butthereweresignificantdifferencesbetweenthehalome...
醫源資料庫;在線期刊;中國熱帶醫學雜誌;2007年第7卷第7期DiagnosticValueofMeasuringEpstein-BarrVirus(EBV)DNALoadandCarcinoma-SpecificViralmRNAinRelationtoAnti-EBVImmunoglobulinA(IgA)andIgGAntib
...CyclerPCR,85.9%ofpatientswerepositiveand60.4%hadlevelsabovetheCOV.ThisassayquantifiedasignificantlyhigherEBVloadthanthe213-bpPCRassay(P0.0001),suggestingthatcirculatingEBVDNAisfragmented.Usingdatafrom11differentstudies,weshowedasignificantinversecorrelationbetweenPCRampliconsizeandthepercentageofpat...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期AProteinToxinfromtheSeaAnemonePhyllodiscussemoniTargetstheKidneyandCausesaSevereRenalInjurywithPredominantGlomerularEndothelialDamage
...nandswellingthatoftentakesmonthstoresolve.2WerecentlyreportedamoreserioussequelaofenvenomationbyP.semoni;thevictimdevelopedunexplainedacuterenalfailurewithoutevidenceofdysfunctionofotherorgans.2Fromhospitalrecordscoveringthelast6yearsintheOkinawaarea,therewereatleastthreeothercaseswithacuterenalfail...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第8期Leptinactionintheforebrainregulatesthehindbrainresponsetosatietysignals
...ton,USA.AbstractThecapacitytoadjustenergyintakeinresponsetochangingenergyrequirementsisadefiningfeatureofenergyhomeostasis.Despitetheidentificationofleptinasakeymediatorofthisprocess,themechanismwherebychangesofbodyadiposityarecoupledtoadaptive,short-termadjustmentsofenergyintakeremainspoorlyunderst...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第3期RegulationofnaturalcytotoxicitybytheadaptorSAPandtheSrc-relatedkinaseFyn
1LaboratoireduDéveloppementNormaletPathologiqueduSystèmeImmunitaire,UnitéInstitutNationaldelaSantéetdelaRechercheMedicale429,HpitalNeckerEnfants-Malades,75015Paris,France2InternationalAgencyforResearchonCancer,69372Lyon,France3ClinicalResearchInstituteofMontréal,Montréal,QuébecH3G146,CanadaSA...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第1期CXCL1inducedbyprostaglandinE2promotesangiogenesisincolorectalcancer
...lanomas,wedeterminedwhetherCXCL1levelsarealsoincreasedinhumanCRCs.Real-timequantitativePCRandELISAassayswereperformedtomeasureCXCL1levelsinhumancoloncarcinomasatgradeII–IIIcomparedwiththematchednormaltissues.CXCL1mRNAlevelswereelevatedin17of20(85%)cancerspecimens(Fig.1A).CXCL1proteinexpressionwasa...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第4期MorphologicFindingsofCoronaryAtheroscleroticPlaquesinDiabetics
...yMedicalCenter,Washington,DC.ABSTRACTObjective—Coronaryatheroscleroticplaquecompositionofdiabeticsubjectsandlocalizationofreceptorforadvancedglycationendproducts(RAGE)anditsligandshavenotbeenextensivelystudied.MethodsandResults—Heartsfromdiabeticsubjectsandage,race,andsex-matchednondiabeticsubje...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第7期