炎症與2型糖尿病的胰島素抵抗
...抗。JNK可以直接使胰島素受體底物(IRS)1的第302位(Ps302)和307位(Ps307)絲氨酸磷酸化,阻斷胰島素信號傳導。激活的NF-κB從胞漿轉位到胞核,可增加TNF-α、IL-6、抵抗素、CRP、PAI-1等表達,從而增加胰島素抵抗,同時促使血管斑塊形成。非類...
行業資訊;臨牀快報;糖尿病相關IdentificationofSolubleTumorNecrosisFactor-LikeWeakInducerofApoptosis(sTWEAK)asaPossibleBiomarkerofSubclinicalAtherosclerosis
...oteinwasidentifiedassolubletumornecrosisfactor-likeweakinducerofapoptosis(sTWEAK).ToconfirmthatsTWEAKwastheproteinofinterest,Westernblotandenzyme-linkedimmunosorbentassaywereperformed.BothtechniquesconfirmedthatsTWEAKlevelsweredecreasedincarotidplaquesupernatants.SubsequentmeasurementofsTWEAKinplasm...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第4期EMB基因330密碼子分子DNA探針設計及熒光檢測
...醇結核分枝桿菌菌株來源於重慶市肺科醫院(42RE\A021E\307E等共33株),金葡菌對照組來源於本科室。按全國結核病細菌學檢驗標準化規程進行分支桿菌培養(Roch培養基)、菌種鑑定和藥敏試驗。滅活條件爲:85℃,1h。採用QIANGEN...
醫源資料庫;在線期刊;局解手術學雜誌;2009年第18卷第1期TopographicBasisofBimodalVentilationeCPerfusionDistributionsduringBronchoconstrictioninSheep
...forassessingagreementbetweentwomethodsofclinicalmeasurement.Lancet1986;327:307eC310.Rodriguez-RoisinR,FerrerA,NavajasD,AgustiAG,WagnerPD,RocaJ.Ventilation-perfusionmismatchaftermethacholinechallengeinpatientswithmildbronchialasthma.AmRevRespirDis1991;144:88eC94.VidalMeloMF,HarrisRS,LayfieldD,MuschG,...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第4期碘-131治療重度甲狀腺腫大甲亢51例臨牀分析
...者進行碘-131治療觀察並隨訪,一次治癒率80.4%,同解放軍307醫院內一科報告的一般甲亢病人應用碘-131治療一次治癒率84.3%[2]相近,二次治癒率16.2%,三次治癒率3.4%。早發甲低爲7.8%,永久性甲低爲3.9%。平均治癒時間僅5.4個月,...
醫源資料庫;在線期刊;中華醫藥雜誌;2005年第5卷第9期EffectofBronchoscopicLungVolumeReductiononDynamicHyperinflationandExerciseinEmphysema
...ieved(9).Reductionsindynamichyperinflationhavebeendemonstratedaftertreatmentwithbronchodilators(10eC12)andafterlungvolumereductionsurgeryorbullectomy(13).BLVRcouldbeexpectedtoreducedynamichyperinflationeitherbycausingtheworstaffectedareasoflungtocollapseorbyexcludingthemfromventilation.Inthepresence...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第3期腹腔鏡膽囊切除3059例臨牀資料回顧分析
...例,佔0.36%。同時合併其他手術(三鏡聯合9例,二鏡聯合307例),闌尾切除術39例,肝囊腫開窗術13例,小腸憩室切除3例,卵巢囊腫切除術21例,子宮肌瘤全子宮切除術4例。本組無死亡及嚴重併發症病例發生。結論採用腹腔鏡膽...
醫源資料庫;在線期刊;中華現代外科學雜誌;2006年第3卷第2期Cardioprotectivec-kit+cellsarefromthebonemarrowandregulatethemyocardialbalanceofangiogeniccytokines
...tology,PrincessMargaretHospitalandOntarioCancerInstitute,UniversityHealthNetwork,UniversityofToronto,Toronto,Ontario,Canada.AbstractClinicaltrialsofbonemarrowstem/progenitorcelltherapyaftermyocardialinfarction(MI)haveshownpromisingresults,butthemechanismofbenefitisunclear.Weexaminedthenatureofendoge...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第7期First-EverStrokeIncidenceand30-DayCaseFatalityintheSicilianAeolianArchipelago,Italy
...ascertainmentbasedonmultipleoverlappingsources,andprospectivestudydesign.1ItwasperformedfromJuly1,1999,toJune30,2002,thankstothefullcooperationofallAeolianphysiciansandGPsinparticular,whoweretrainedtofillinaclinicalscheduletonotifytheteamofsuspectedstrokecases.Wheneverpossible,patientswerehospitaliz...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第12期RoleoftheInterleukin-6–174GCGenePolymorphisminRetinalArteryOcclusion
...etinalarteryocclusion(RAO).Methods—Onehundredeighty-twopatientswithRAOand307controlsubjectsweregenotypedfortheIL-6–174GCpolymorphism.Genotypesweredeterminedbyfluorogenicexonuclease(TaqMan)assay.Results—TheprevalenceoftheCCgenotypewassignificantlylowerinpatientswithRAOthanincontrolsubjects(10.4...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第2期