MutationsinlipidtransporterABCA12inharlequinichthyosisandfunctionalrecoverybycorrectivegenetransfer
...ingcause.Abnormalkeratinocytelamellargranules(LGs)areahallmarkofHIskin.ABCA12isamemberoftheATP-bindingcassettetransporterfamily,andmembersoftheABCAsubfamilyareknowntohavecloselyrelatedfunctionsaslipidtransporters.ABCA3isinvolvedinlipidsecretionviaLGsfromalveolartypeIIcells,andmissensemutationsinABCA...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第7期VitaminB-12andfolatedeficiencyinelderlypersons
...dStandardsAgencywasinfluencedbyarecentlycompletedstudyclaimingthatvitaminB-12deficiencyamongtheelderlyismorecommonthanhadbeenpreviouslysuspected.TheinvestigatorslinkedthisclaimtothetheoreticalconcernthatfolicacidfortificationmightdelaythediagnosisofvitaminB-12neuropathyorevenprecipitateitsonset.Ther...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第2期TheRegulatorofGProteinSignalingDomainofAxinSelectivelyInteractswithG12butNotG13
...andincellsthatthisdomaininteractswiththesubunitoftheheterotrimericGproteinG12butnotwiththecloselyrelatedG13orwithseveralotherheterotrimericGproteins.AxinpreferentiallybindstheactivatedformofG12,abehaviorconsistentwithotherRGSproteins.However,unlikeotherRGSproteins,thatofaxin(axinRGS)doesnotaffectint...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第10期肥胖的辨證治療
...健脾補腎。 健脾補腎湯:黨蔘30克,黃芪30克,黃精12克,山藥20克,山萸肉12克,澤瀉12克,蓮子12克,炒薏苡仁20克,芡實15克,茯苓12克,白朮12克,制附子6克,生薑3克,白芍12克,山楂12克,補骨脂15克,沙苑子15克,甘草6...
中醫中藥;中醫臨牀;辯證施治Extentofthermalprocessingofinfantformulaaffectscopperstatusininfantrhesusmonkeys
...e5mo,infantmonkeys(n=6/group)werefedoneofthefollowingformulasexclusively:1)12mgFe/Lprocessedincans(RTF-12),2)formulainglassbottleswith12mgFe/Landmanufacturedbyanultrahigh-temperature(UHT)process(UHT-12),or3)formulamanufacturedbyastandardthermalprocess(STP),containingeither8(STP-8)or12(STP-12)mgFe/L....
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2001年73卷第5期轉染雙啓動子桿狀病毒表達載體在昆蟲細胞共表達人白細胞介素12
...啓動子桿狀病毒表達載體在昆蟲細胞共表達人白細胞介素12中華微生物學和免疫學雜誌2000年第6期第20卷細胞因子作者:魏海明 田志剛 馮進波 徐彤 夏菁 孫單位:山東省醫學科學院基礎醫學研究所,山東腫瘤生物治療研究...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學PreventionofUVradiation–inducedimmunosuppressionbyIL-12isdependentonDNArepair
...rmatology,UniversityKiel,D-24105Kiel,GermanyTheimmunostimulatorycytokineIL-12isabletoantagonizeimmunosuppressioninducedbysolar/ultraviolet(UV)radiationviayetunknownmechanisms.IL-12wasrecentlyfoundtoinducedeoxyribonucleicacid(DNA)repair.UV-inducedDNAdamageisanimportantmoleculartriggerforUV-mediatedim...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第2期LipidInflammatoryMediatorsinDiabeticVascularDisease
...andcytokines.Thisreviewhighlightstherolesoftheinflammatorycyclooxygenaseand12/15-lipoxygenasepathwaysinthepathogenesisofdiabeticvasculardisease.Evidencesuggeststhatinflammatoryresponsesinthevasculaturecanbeelicitedbysmalloxidizedlipidsthatarecomponentsofoxidizedlow-densitylipoproteinorproductsofthel...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第9期ReplytoNJWaldetal
...tofClinicalGeratologyRadcliffeInfirmaryOxfordUnitedKingdomDearSir:VitaminB-12deficiencycausedbyeitherintrinsicfactordeficiencyorhypochlorhydriachieflyaffectstheelderly.VitaminB-12deficiencymaypresentasmacrocyticanemia,butitalsocausesneuropathy,including(ifthedeficiencyissevere)subacutecombineddegene...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第2期胸12椎體腰化
【摘要】目的探討胸12椎體腰化的一些共同點。方法收集本院1年多來在CT檢查過程中發現脊柱移行異常時,進行從頸1椎體向下的X線透視下或攝全脊柱片計數確定爲胸12椎體腰化的患者。結果在19例胸12椎體腰化的患者中有12例爲女...
醫源資料庫;在線期刊;中華現代影像學雜誌;2009年第6卷第11期