A20-YearProspectiveCommunityStudy
...tudieshavebeenlimitedintheirabilitytoincreaseourunderstandingofthesemechanismsbecauseofverydifferentdefinitionsofpanicandlackofinformationaboutthetemporalassociationbetweenasthmaandpanic.Todate,onlyonebrief(1year)longitudinalcommunity-basedstudyonasthmaandpanicinadults(6)hasbeenpublished,whichreport...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第6期ModulationofFactorVLevelsinPlasmabyPolymorphismsintheC2Domain
...100Ferrara,Italy.E-mailber@unife.itAbstractObjective—Functionalpolymorphismscontributingtocoagulationfactorlevelsarepreferentialmarkersforassociationstudiesaimedatidentifyingprothrombicgeneticcomponents.MethodsandResults—FactorV(FV)microsatellitegenotypeswerefoundtobeassociatedwithFVlevels(P=0.0...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第1期PolymorphismsintheCD14GeneAssociatedwithPulmonaryFunctioninFarmers
...lex.Engagementofthiscomplexresultsintheactivationofinnatehostdefensemechanismssuchasreleaseofproinflammatorycytokines.SolubleCD14(sCD14)isfoundinnormalplasmaatmicrogramconcentrations(15)andhasbeenshowntobeelevatedinthelungasaresultofinflammation(16),infection(17,18),orallergenprovocation(19).Thegene...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第4期HemodynamicRegulationofCD34+CellLocalizationandDifferentiationinExperimentalAneurysms
...ssiveaorticdiameterenlargementandeventualrupture.5SpecificbiologicalmechanismsrelatedtoAAAinitiation,growth,andeventualruptureremainspeculativeandhighlycontroversial.6Bloodflowandwallshearstress(WSS)valuesvaryalongthelengthofthehumanaortafromthediaphragmtotheaorticbifurcation.Comparedwithmoreproxima...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第10期GeographicDiversityamongGenotypesofEntamoebahistolyticaFieldIsolates
...yticafieldisolatesinnature.Inthepresentstudy,weanalyzedthegeneticpolymorphismsoftwononcodingloci(locus1-2andlocus5-6)andtwoprotein-codingloci(chitinaseandserine-richE.histolyticaprotein[SREHP])among79isolatesobtainedfromdifferentgeographicregions,mainlyJapan,Thailand,andBangladesh.Whenthegenotypesof...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期含砷化物中藥及製劑的分子藥理學研究進展
...20ChenGQ,ZhuJ,ShiXG,etal.Invitrostudiesoncellularandmolec-ularmechanismsofarsenictroxide(As2O3)inthetreatmentofacutepromyelocyticleukemia:As2O3inducesNB4cellapoptosiswithdown-regulationofBcl-2expressionandmodulationofPML-RARα/PMLproteins.Blood,1996,88(3):1052-1059. 21蔡循...
合作平臺;在線期刊;中華現代臨牀醫學雜誌;2005年第3卷第9期DifferentialDistributionandExpressionofPanton-ValentineLeucocidinamongCommunity-AcquiredMethicillin-ResistantStaphylococcusaureusStrains
...rmedandtheresultswereinterpretedasdescribedpreviously(33).Briefly,theorganismswereembeddedinagarose,andtheintactchromosomewasdigestedwithSmaI.DNAfragmentswereresolvedfor22hwithaBio-RadCHEFDR-IIPFGEunit(Bio-Rad,Hercules,CA).agrtyping.theS.aureusstrainswereanalyzedfortheiragrtypesbythemethodofJarraude...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期SpecificandSensitiveDetectionofNeisseriagonorrhoeaeinClinicalSpecimensbyReal-TimePCR
...iedsequenceintheopagenes.TestingalargepanelofrelatedandunrelatedmicroorganismsrevealedthatotherNeisseriastrainsandothermicroorganismstestednegativeintheopatest.Withalowerdetectionlimitofonegenomeperreaction,theopatestappearedmoresensitivethanboththeCOBASAMPLICOR(RocheDiagnosticsNederlandBV,Almere,Th...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期ShearStressIncreasesICAM-1andDecreasesVCAM-1andE-selectinExpressionsInducedbyTumorNecrosisFactor-inEndothelialCells
...gandpostshearingontheTNF-–inducedgeneexpressionsarenotadditive.ThemechanismsbywhichshearstressexertsdifferentialeffectsontheTNF-–inducedICAM-1versusVCAM-1andE-selectinexpressionsinECsremainunclear.Cytokinesandmechanicalforcesarewellknownmediatorsofgeneexpressionincellsviaactivationoftranscriptio...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第1期EndothelialOverexpressionofFasLigandDecreasesAtherosclerosisinApolipoproteinE–DeficientMice
...ialeffectoftheFasLtransgeneonlymphocyteinfiltration.Thereareatleast2mechanismsthatcouldaccountfortheantiatherogeniceffectofendothelialFasLintheTgmodel.OnepossibilityisthatendothelialcellsoverexpressingFasLonthesurfaceinduceapoptosisincellsthatcomposethelesion.Forexample,endothelialcellsmayshedFasL,w...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第8期