cAMP-dependentstabilizationofphosphoenolpyruvatecarboxykinasemRNAinLLC-PK1-F+kidneycells
...ycline-responsivepromotersystemwasusedtoquantifytheeffectofforskolinonthehalf-livesofchimeric-globin-PEPCK(TG-PCK)mRNAs.Thehalf-lifeofthelabileG-PCK-1mRNAwasincreasedeightfoldbyadditionofforskolin.Incontrast,thehalf-livesoftheconstructscontainingtheindividualinstabilityelementswereincreasedonlytwofo...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第3期炭疽病
...子(致死因子,LF)所組成的複合多聚體。3種成分個別注入動物體內均無毒性,但保護性抗原加水腫因子或致死因子則可分別引起水腫、壞死或動物死亡。【發病機理】當一定數量的芽胞進入皮膚破裂處,吞入胃腸道或吸入呼吸...
求醫問藥;疾病手冊;感染與傳染病科Effecton24-henergyexpenditureofamoderate-fatdiethighinmonounsaturatedfattyacidscomparedwiththatofalow-fat,carbohydrate-richdiet:a6-moc
...eoxidationaftera6-mocontrolleddietaryinterventionwitheitheraMUFAoralow-fat(LF)diet.Design:Twenty-sevenoverweight[bodymassindex(inkg/m2):28.1±0.4]nondiabeticsubjectsaged1836yfollowedan8-wklow-caloriedietanda2-wkweight-stabilizingdietandthenwererandomlyassignedtoaMUFA(n=12)orLF(n=15)dietfor...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年85卷第4期Geneexpressionprofilinggetstotherootofhumanhairfolliclestemcells
...estomicrodissectoutbulgecells.Theydiscoveredapanelofcellsurfacemarkersusefulforisolatinglivinghairfolliclestemcells,afindingwithpotentialtherapeuticimplicationssinceisolatedstemcellsinmicecangeneratenewhairfollicleswhentransplantedtoothermice.ThefindingsofOhyamaetal.validatetheuseofthemouseforstudyi...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第1期灌注CT成像在超早期腦梗死疾病中的研究
...T掃描及灌注成像。1.2設備美國GE公司HispeedCT/I、NX/I,高瑪LF9000CT專用高壓注射器、ULTRASANAW4.1工作站。1.3層面選擇首先行頭顱常規平掃檢查,從顱底掃描至頂層厚10mm,層間距10mm。然後選取基底節及其相鄰層面,其內儘量包含病變...
醫源資料庫;在線期刊;中華現代影像學雜誌;2007年第4卷第6期Globalanalysisofproliferationandcellcyclegeneexpressionintheregulationofhematopoieticstemandprogenitorcellfates
...tinctsetsofcellcycleproteinsthatspecificallyassociatewithdifferentiation,self-renewal,andmaintenanceofquiescenceinHSCandprogenitorcells.Moreover,wedescribeastrikinginequalityoffunctionamonginvivocyclingandquiescentHSCbydemonstratingthattheirlong-termengraftmentpotentialresidespredominantlyintheG0fra...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第11期自擬白蘇湯治療化療引起的白細胞減少症初步研究
...P;乳腺癌:CMF、CAF、CAP、EAP;食道癌:DF、PVB;結、直腸癌:DF、HLF、HDLF、LF;卵巢癌:CP、CAP、EP;絨癌:PVB;子宮內膜癌:EPF、AP;白血病:DA;惡性淋巴瘤:CHOP、COP;膀胱癌:MMC或ADM灌注;多發性骨髓瘤:VAD或M2。1.4方法自擬白蘇湯方,藥用:黨蔘、黃芪...
合作平臺;在線期刊;中華現代中西醫雜誌;2004年第2卷第12期;中醫中藥IL-1receptor–associatedkinaseMisacentralregulatorofosteoclastdifferentiationandactivation
...sassociatedwiththeaccelerateddifferentiationofosteoclasts,anincreaseinthehalf-lifeofosteoclasts,andtheiractivation.LigationofIL-1RorTLRsresultsinhyperactivationofNF-Bandmitogen-activatedproteinkinasesignalingpathways,whichareessentialforosteoclastdifferentiation.Thus,IRAK-Misakeyregulatorofthebonelo...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第7期低電流針刺對輕度高血壓患者的壓力反射敏感性分析
...者的BRS降低不僅表現在總頻段(TF),而且在極低頻段(VLF0.046Hz)、低頻段(LF0.046~0.16Hz)、高頻段(HF0.16~0.53Hz)均降低。與文獻報道一致[4]。HBRS反映壓力反射弧快迷走介導支的特性;LBRS反映壓力反射弧快迷走介導支及慢...
醫源資料庫;在線期刊;中華醫學實踐雜誌;2006年第5卷第10期上海市松江區2005-2007年兒童傳染病疫情分析
...primary,secondaryschoolstudentsandpreschoolchildrenwillbewillingtoreceiveselfpaidvaccinations.【Keywords】Communicablediseases;Prevalence;Epidemiologicstudies;Child 兒童青少年的健康是當今社會關注的重點問題之一。國內相關研究表明,傳染病是影響兒童青...
醫源資料庫;在線期刊;中國學校衛生;2009年第29卷第1期