ResveratrolSuppressesTumorNecrosisFactor--InducedFractalkineExpressioninEndothelialCells
...nducedfractalkinemRNAandproteinexpressioninendothelialcells.ResveratrolstronglysuppressedTNF--inducedfractalkineexpressioninendothelialcellsthroughsuppressionofnuclearfactor-BandSp1activities.ResveratroldecreasedthenumberofTNF--inducedfractalkine-positiveendothelialcellsandCX3CR1-positivecellsdeterm...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第7期MatrixMetalloproteinase2ActivationofTransformingGrowthFactor-ß1(TGF-ß1)andTGF-ß1-TypeIIReceptorSignalingWithintheAgedArteri
...要】Objective-Tostudymatrixmetalloproteinase2(MMP-2)effectsontransforminggrowthfactor-ß1(TGF-ß1)activationstatusanddownstreamsignalingduringarterialaging.MethodsandResults-WesternblottingandimmunostainingshowedthatlatentandactivatedTGF-ß1aremarkedlyincreasedwithintheaortaofagedFi...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第7期FailureofHigh-DoseErgocalciferoltoCorrectVitaminDDeficiencyinAdultswithCysticFibrosis
...,Baltimore,MarylandABSTRACTRationale:TreatmentguidelinesforvitaminDmonitoringandsupplementationincysticfibrosis(CF)haverecentlybeendevelopedandpublishedbyaconsensuscommittee,buthavenotbeenprospectivelytested.Objectives:TousetheseguidelinestodeterminethepercentageofadultswithCFrequiringvitaminDreplet...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第7期丹蔘酮ⅡA對兔纖維環細胞能量代謝的保護作用
...爲空白對照不加入藥物,B組加入4μg/mlTSⅡA,C組加入10ng/mlIL-1β,D~G組在給予10ng/mlIL-1β同時分別加入0.5、1、2和4μg/mlTSⅡA。於培養3d後行Na+-K+-ATP酶活性檢測、,琥珀酸脫氫酶活性檢測、MTT法細胞增殖情況檢測以及細胞凋...
醫源資料庫;在線期刊;中國矯形外科雜誌;2009年第17卷第21期ControlleddeliveryofPDGF-BBformyocardialprotectionusinginjectableself-assemblingpeptidenanofibers
...thatprotectionofcardiomyocytesbyendothelialcellsoccursthroughPDGF-BBsignaling.PDGF-BBinducedcardiomyocyteAktphosphorylationinatime-anddose-dependentmannerandpreventedapoptosisviaPI3K/Aktsignaling.Usinginjectableself-assemblingpeptidenanofibers,whichboundPDGF-BBinvitro,sustaineddeliveryofPDGF-BBtothe...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第1期RaisedPlasmaSolubleP-SelectininPeripheralArterialOcclusiveDiseaseEnhancesLeukocyteAdhesion
...clear.InthisstudywehaveexaminedapotentialroleforplasmasP-selectininregulatingneutrophiladhesioninpatientswithperipheralarterialocclusivedisease(PAOD).PatientswithPAODhadsignificantlyhigherlevelsofsP-selectin(mean±SD:73.3±13.0versus16.7±6.4ng/mL)andenhancedwholebloodleukocyteadhesiontoplateletsund...
醫源資料庫;在線期刊;循環研究雜誌;2006年第96卷第1期利培酮和氟哌啶醇的臨牀對照研究
...0例)、氟哌啶醇組(33例)患者的基線SOD濃度[(794±126)ng/mgHb,(750±101)mg/mgHb]均明顯高於正常對照組[(483±110)ng/mgHb],而PRL濃度[(6±7)μs/L,(6±8)μg/L]均明顯低於正常對照組[(18±12)μg/L],差異均有統計學意...
行業資訊;臨牀快報;神經科杜仲葉醇提物預防去勢大鼠骨質疏鬆症的實驗研究
...生物杜仲/治療作用杜仲葉醇大鼠 AnexperimentstudyofDuzhongyechuninpreventionofosteoporosisonovariectomizedfamalerats BAIli-wei,WENGXiao-gang,SUOXin-hua,etal (DepartmentofendocrinologyofthefirstaffiliatedhospitalofXinxiangMedicalCollege,Henan453100,China)【Abstract】Objec...
醫源資料庫;在線期刊;中國民康醫學;2008年第20卷第15期FunctionalArterialandVenousFateIsDeterminedbyGradedVEGFSignalingandNotchStatusDuringEmbryonicStemCellDifferentiation
...ctive-Theaimofthisworkwastodevelopamouseembryonicstem(ES)cellsystemaddressingtheearlyspecificationofthedevelopingvasculatureintofunctionalarteriesandveins.MethodsandResults-EScellsweredifferentiated4daysoncollagen-typeIVcoateddishestoobtainFlk1+endothelialprecursors.Sub-cultureoftheseprecursorsforad...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第3期AnalysisoftheAbilityofSpirocheteSpeciesAssociatedwithRelapsingFeverAvianBorreliosis,andEpizooticBovineAbortionToBindFactorHandCleaveC3b
...asion.InthisreportwedemonstratethatsomeBorreliaspeciesassociatedwithrelapsingfeverbindfH,butnotthoseassociatedwithavianborreliosisandepizooticbovineabortion.Cell-boundfHwasalsofoundtomediatecleavageofexogenouslysuppliedhumanC3b,demonstratingthebiologicalrelevanceoffHbindinganditspossibleimportancein...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期