DomainsNecessaryforG12BindingandStimulationofProteinPhosphatase-2A(PP2A):IsG12aNovelRegulatorySubunitofPP2A?
...cellsstimulatedPP2Aactivityasdeterminedbydecreasedphosphorylationoftyrosine307onthecatalyticsubunit.BasedoncrystalstructuresofG12andPP2AA,amodeldescribingthebindingsurfacesandpotentialmechanismsofG12-mediatedPP2Aactivationispresented.HeterotrimericGproteinsregulatefundamentalprocessesinalleukaryotic...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第5期ChagasDiseaseIsanIndependentRiskFactorforStroke
...gforthediseaseinstrokepatientsisnotroutinepractice.Recently,anassociationbetweenvariousinfectiousagentsandstrokehasbeendescribed.4,5InCD,strokehasbeenidentifiedinpatientswithoutclinicalsignsofcardiopathy,6raisingthepossibilityofotheroperativemechanisms.Inthepresentstudy,weaimedtodescribepredictorsof...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第9期TNF-PromoterPolymorphismsandSusceptibilitytoHumanPapillomavirus16AssociatedCervicalCancer
...y[16].Inthepromoterregionofthegene,theSNPsthataffecttranscriptionofTNF-are-307[17,18],-375[19],-863[18,20],and-857[20].AlteredlevelsofTNF-mayinfluencetheimmuneresponsetopathogensandcontributetoanindividual‘ssusceptibilitytodisease.Inthatregard,somepolymorphismsintheTNF-genehavebeenassociatedwithsu...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第6期TransmembraneDomainVIIoftheHumanApicalSodium-DependentBileAcidTransporterASBT(SLC10A2)LinestheSubstrateTranslocationPathway
...e(MTSES)]ofmutantswereevaluatedinCOS-1cells.Thr289,Tyr293,Gln297,Ala301,Phe307,andTyr308representedloss-of-functionmutants;furthermore,themeasurableresidualactivitiesforT289C,Y293C,andA301C(20%control)provedinsensitivetoMTStreatment.MTSESandMTSETinhibitionwasconfinedtoresiduesliningtheextracellularh...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第11期Identification,MolecularCharacterization,andExperimentalTransmissionofaNewHemoplasmaIsolatefromaCatwithHemolyticAnemiainSwitzerland
...umandpiroplasmidsincatsfromsouthernEurope:amolecularstudy.Vet.Microbiol.93:307-317.Flint,J.C.,M.H.Roepke,andR.Jensen.1959.Felineinfectionsanemia.II.Experimentalcases.Am.J.Vet.Res.20:33-40.Foley,J.E.,S.Harrus,A.Poland,B.Chomel,andN.C.Pedersen.1998.Molecular,clinical,andpathologiccomparisonoftwodistin...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第6期藥物篩選研究發現:蓮子心有望用於治療肺纖維化
本報北京訊日前,中國人民解放軍307醫院通過對赤芍、毛冬青、蓮子心、瑞香狼毒、貓眼草、千金子、蒲公英7種中草藥的篩選,證實蓮子心是一種有希望的治療肺纖維化的苗頭藥物。 目前,對於肺纖維化臨牀上缺乏有效的...
醫學教育;科教新聞PretreatmentwithLactobacillus-andBifidobacterium-containingyogurtcanimprovetheefficacyofquadrupletherapyineradicatingresidualHelicobacterpylo
...K),Pathology(H-BY),andMedicalTechnology(J-JW),theInstituteofPublicHealth(S-TW),andtheInstituteofClinicalMedicine(B-SS,H-CC,andY-JY),MedicalCollege,NationalChengKungUniversity,Tainan,Taiwan2Supportedbyresearchgrant93-2314-B-006-089and93-2314-B-006-011fromtheNationalScienceCouncil,Taiwan.3Addressrepri...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年83卷第4期Measurementofmagnesiumabsorptionandretentionintype2diabeticpatientswiththeuseofstableisotopes
...ineralabsorptionwithstableisotopetracersinhumansubjects.JAmCollNutr1993;12:30715.BinghamS,CummingsJH.Theuseof4-aminobenzoicacidasamarkertovalidatethecompletenessof24hurinecollectionsinman.ClinSci(Lond)1983;64:62935.BinghamSA,CummingsJH.Theuseofcreatinineoutputasacheckonthecompletenessof2...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年78卷第3期Autologousserumeyedropsforocularsurfacedisorders
...teeforStandardsinHaematologyBloodTransfusionTaskForce.TransfusionMed1993;3:307–16.ThomasL.LaborundDiagnose.5.Auflageed:TH-Books,1998:1494.DugrillonA,LauberS,NguyenXD,etal.Plateletsappliedtowoundsandintissueregeneration:inductionofproliferationapoptosisbyplateletmembranes.In:MempelW,SchrammW,eds.In...
醫源資料庫;在線期刊;英國眼科學雜誌;2004年第88卷第11期氣管插管在院前急救中的應用
...eof3groups.ResultsOpportunityoftrachealintubationhasclinicalsignificancebe-tween30minutesgroupandover1hourgroup.ConclusionThetimeoftrachealintubationofsevereheadinjurypa-tientsasearlyaspossibleinpre-hospitalemergencycansignificantlyincreasepatients‘outcome. 【Keywords】severeheadinjurypre-h...
合作平臺;在線期刊;中華現代臨牀醫學雜誌;2005年第3卷第13期