Megalinbindsandinternalizesangiotensin-(1-7)
...an(13%)(P0.001).Inanalysisbyflowcytometryofbindingexperimentsperformedinbrush-bordermembranevesiclesisolatedfromkidneysofCD-1mice,anti-megalinantiserainterferedwithANG-(1-7)bindingmorestronglythanolmesartan(P0.05againstpositivecontrol).InteractionsofmegalinwithANG-(1-7)atamolecularlevelwerestudiedby...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第5期SimpleMethodforDeterminationoftheNumberofHelicobacterpyloriCagAVariable-RegionEPIYATyrosinePhosphorylationMotifsbyPCR
...ableregionoftheprotein.StrainspossessingCagAwithgreaternumbersoftheserepeatshavebeenmorecloselyassociatedwithgastriccarcinogenesis.PhosphorylatedCagAleadstoepithelialcellelongation,whichisdependentonthenumberofvariable-regionEPIYAmotifs.Thus,determinationofthedegreeofCagAphosphorylationandthenumbero...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期高效液相色譜法測定何首烏及制首烏中羥芪衍生物的含量
...多以蒽醌類作爲含量指標。由於其含有的蒽醌類成分,如大黃素、大黃酚等在同屬大黃、虎杖等藥材中也含有,因此作爲指標成分專屬性較差。 在何首烏質量標準研究中,我們分離、鑑定了其中含量較高的羥芪類成分—2,3...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例Cognitiveaging,childhoodintelligence,andtheuseoffoodsupplements:possibleinvolvementofn3fattyacids
...eAlzheimer‘sResearchTrust.LJWholdsaWellcomeTrustCareerDevelopmentAward.JMSholdsaHealthFoundationLeadingPracticeThroughResearchAward.IJDisarecipientofaRoyalSocietyofLondonWolfsonResearchMeritAward.3Reprintsnotavailable.AddresscorrespondencetoLJWhalley,DepartmentofMentalHealth,ClinicalResearch...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第6期第三節 細胞因子受體
...含絲氨酸區與非激酶信賴途徑有關。IL-2Rγ鏈胞漿區具有SH2結構,參與信號傳遞。細胞漿中的PTK和PKC可能參與IL-4R介導的信號傳遞。gp130胞漿區絲氨酸富含區以及酷氨酸磷酸化與gp130介導的信號轉導有關。此外,酪氨酸磷酸化與IL-7R...
醫源資料庫;醫源圖書館;教材類;細胞和分子免疫學NoonanSyndromeMutationQ79RinShp2IncreasesProliferationofValvePrimordiaMesenchymalCellsviaExtracellularSignaleCRegulatedKinase1/2Signaling
theCincinnatiChildren’sHospitalMedicalCenter,DivisionofMolecularCardiovascularBiology,Cincinnati,Ohio.AbstractThemolecularpathwaysregulatingvalvedevelopmentareonlypartiallyunderstood.Recentstudiesindicatethatdysregulationofmitogen-activatedproteinkinase(MAPK)signalingmightplayamajorroleinthepathog...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第10期HPLC法測定新生化顆粒中阿魏酸含量及有關物質TLC方法的研究
...製備方法分別製備6份樣品溶液,按上述色譜條件測定,大黃素含量RSD爲0.97%,重複性良好。 2.7.8加樣回收率試驗精密吸取已知含量(0.0486ml/g)的新生化顆粒樣品,加入一定量的對照品溶液,按上述同等色譜條件測定阿魏酸的回...
醫源資料庫;在線期刊;中華醫藥雜誌;2010年第10卷第3期MelatoninIsNeuroprotectiveinExperimentalStreptococcuspneumoniaeMeningitis
...edbytreatmentwithmelatonininorganotypichippocampalcultures(P.001)andinhumanSH-SY5Ycells(P.01).RabbitswereinfectedintracisternallywithStreptococcuspneumoniaeandreceivedeithermelatonin(20mg/kgbodyweight/24h;n=12)orsaline(n=11)intravenously.Twelvehourslater,allrabbitsreceivedceftriaxone(10mg/kgbodyweig...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第5期TargetedHybridizationofIS6110FingerprintsIdentifiestheW-BeijingMycobacteriumtuberculosisStrainsamongClinicalIsolates
...lates,theW-Beijingstrainfamily,hasreceivedconsiderableattention.ThesestrainshavebeenshowntobehighlyprevalentthroughoutAsiaandthecountriesoftheformerSovietUnion,andtheyhavebeenassociatedwithnosocomialandcommunityoutbreaks,globaltransmission,anddrugresistance(3,10,28).TheW-Beijingstrainshavebeenalsoas...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第5期LeishmaniaPromastigoteMembraneAntigen-BasedEnzyme-LinkedImmunosorbentAssayandImmunoblottingforDifferentialDiagnosisofIndianPost-Kala-AzarDermal
...ofTropicalMedicine,Calcutta,IndiaABSTRACTDiagnosisofpost-kala-azardermalleishmaniasis(PKDL),causedbyLeishmaniadonovani,isdifficult,asthedermallesionsareofseveraltypesandresemblethosecausedbyotherskindiseases,especiallyleprosy.Sincethediseasegenerallyappearsverylateaftertheclinicalcureofkala-azarinIn...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第3期