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TransmembraneDomainVIIoftheHumanApicalSodium-DependentBileAcidTransporterASBT(SLC10A2)LinestheSubstrateTranslocationPathway
...ylsulfonate(MTSES)]ofmutantswereevaluatedinCOS-1cells.Thr289,Tyr293,Gln297,Ala301,Phe307,andTyr308representedloss-of-functionmutants;furthermore,themeasurableresidualactivitiesforT289C,Y293C,andA301C(20%control)provedinsensitivetoMTStreatment.MTSESandMTSETinhibitionwasconfinedtoresiduesliningtheextr...
醫源資料庫；在線期刊；分子藥理學雜誌；2006年第68卷第11期 -
Mass-SpectrometricIdentificationofaNovelAngiotensinPeptideinHumanPlasma
...nalfailurepatients.MethodsandResults-Chromatographicpurificationandstructuralanalysisbymatrix-assistedlaserdesorption/ionisationtime-of-flight/time-of-flight(MALDI-TOF/TOF)revealedanangiotensinoctapeptidewiththesequenceAla-Arg-Val-Tyr-Ile-His-Pro-Phe,whichdiffersfromAngIIinAla1insteadofAsp1.Des[Asp1...
醫源資料庫；在線期刊；動脈硬化血栓血管生物學雜誌；2007年第27卷第2期 -
Postprandialeffectofn–3polyunsaturatedfattyacidsonapolipoproteinB–containinglipoproteinsandvascularreactivityintype2diabetes
...nFHilpert,SheilaGWest,PennyMKris-Etherton,KariDHecker,NancyMSimpsonandPetarAlaupovic1FromtheDepartmentsofNutritionalSciences(KFH,PMK-E,andKDH)andBiobehavioralHealth(SGW)andTheHuckInstitutesoftheLifeSciences(KFH),PennsylvaniaStateUniversity,UniversityPark,PA;Frito-Lay,Inc,Plano,TX(KDH);andtheLipidand...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2007年85卷第2期 -
劉偉：生物多樣性數據共享現狀和建議
...據資源共享。澳大利亞2010年10月啓動AtlasofLivingAustralia（ALA），近兩年在生物多樣性數據共享方面取得重要進展。雖是GBIF的澳大利亞節點，但ALA允許個人用戶提交共享數據，這是一個重要進步。資助機構和研究機構也開始採取數...
醫藥經濟；生物技術；技術要聞 -
OrphaninFQ/NociceptinPotentiates[D-Ala2,N-Me-Phe4,Gly5-ol]-EnkephalineCInducedeOpioidReceptorPhosphorylation
DepartmentofPharmacologicalandPharmaceuticalSciences,UniversityofHouston,CollegeofPharmacy,Houston,TexasAbstractInthisstudy,weinvestigatethemolecularmechanismsbywhichacuteorphaninFQ/nociceptin(OFQ/N),actingthroughthenociceptinopioidpeptide(NOP)receptor,desensitizesthee?opioidreceptor.Wedescribedprev...
醫源資料庫；在線期刊；分子藥理學雜誌；2006年第68卷第2期 -
Biochemicaleffectsofadietcontainingfoodsenrichedwithn-3fattyacids
...son,MarkANeumann,MaryanneDemasiandMichaelJJames1FromtheRheumatologyUnit,RoyalAdelaideHospital,Adelaide,Australia,andtheChildNutritionResearchCentre,FlindersMedicalCentre,BedfordPark,Australia.2SupportedbyMeadowLeaFoods/GrainResearchDevelopmentCorporationNutritionalResearchProgram.Thedietaryproductsu...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2000年72卷第1期 -
Prostaglandin-InducedActivationofNociceptiveNeuronsviaDirectInteractionwithTransientReceptorPotentialA1(TRPA1)
...recentdiscoverythatthenociceptor-specificionchanneltransientreceptorpotentialA1(TRPA1)canbeactivatedbyexogenouselectrophilicirritantsthroughdirectcovalentmodification,wereasonedthatelectrophiliccarbon-containingA-andJ-seriesprostaglandins,metabolitesofprostaglandins(PG)E2andD2,respectively,wouldexci...
醫源資料庫；在線期刊；分子藥理學雜誌；2008年第70卷第2期 -
ACEI和ARB與高血壓及相關疾病的合理治療
...用作用不被AT1和AT2受體拮抗劑抑制特異性受體拮抗劑：D-Ala－Ang-(1-7)特異性受體：AT（1-7）受體JosephL,etal.HypertensionPrimer.3rded.LippincottWilliamsWilkins.Dallas,2003.11-12.Ang-(1-7)的代謝途徑肽鏈內切酶AngI(10肽)Ang-(1-7)Ang-(1-7)Ang-(1-5)來源：降解...
醫源資料庫；醫學文檔庫；心血管相關 -
DifferentialexpressionofnuclearAT1receptorsandangiotensinIIwithinthekidneyofthemalecongenicmRen2.Lewisrat
...LewisratsmayreflectacompensatoryresponsetodampentheelevatedlevelsofintrarenalANGII.【關鍵詞】ANGIItypereceptorhypertensionintrarenalangiotensinrenalcortexrenalmedullaANGIITHEINFLUENCEoftherenin-angiotensinsystem(RAS)onthedevelopmentandprogressionofhypertensionandrenalinjuryiswithoutdispute.Itis...
醫源資料庫；在線期刊；美國生理學雜誌；2006年第289卷第6期 -
第三節 遺傳性載脂蛋白代謝異常
...uBaltinore 13：Arg→TyrYame 26：Gly→ArgLowa家族性澱粉樣37：Ala→Thr 89：Asp→Glu 100：Tyr→HisKaratsu 103：Asp→GluMunster3A 107：Lys→0Marbarg(Munster2A)LCAT活性降低107：Lys→Met 108：Trp→ArgTsushima 110：Glu→LysNorway 118：Lys→MetHita...
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