清華大學最新《PNAS》文章
...類方法所取代,有些如酪蛋白蛋白激酶,只是由於習慣而一直被沿用下來。廣義神經遺傳分析(Extensiveneurogeneticanalysis)認爲記憶的形成嚴格依賴於PKA信號通路,但是有關這一通路在記憶形成過程中的詳細細節至今並不清楚。在...
醫藥經濟;生物技術;技術要聞Anti-CD63antibodiessuppressIgE-dependentallergicreactionsinvitroandinvivo
...extracellularmatrix(ECM)proteins.Thesignalsinvolvedinthismodulationaremostlyunknownandtheircontributiontoallergicreactionsinvivoisunclear.HerewereportthegenerationofmonoclonalantibodiesthatpotentlysuppressFcRI-induceddegranulation,butnotleukotrienesynthesis.Weidentifiedtheantibodytargetasthetetraspa...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第3期TransmissionandaccumulationofCTLescapevariantsdrivenegativeassociationsbetweenHIVpolymorphismsandHLA
...yrepresentsanescapemutationfromtheWTKF9/83A,drivenbytargetingofthepreviouslyundescribedHLA-B*57/5801-restrictedepitope,KF9.ThisKF9/83GmutationistransmittedandpersistsintheabsenceofHLA-B*57/5801,andasaresult,itssubsequentaccumulationatthepopulationlevelhasleadtoreplacementofAlabyGlyastheconsensussequ...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第6期Six-MonthMulticenterStudyonInvasiveInfectionsDuetoStreptococcuspyogenesandStreptococcusdysgalactiaesubsp.equisimilisinArgentina
...midase,leucineaminopeptidase,andbacitracinsusceptibilitytestswereperformedbyusingBritaniadisks(BuenosAires,Argentina).Theobservationofchainswasperformedingramsmearspreparedwithdropsofovernightculturesinthioglycolatebroth.Identificationandgroupingwerecompletedbyusingthelatexagglutinationmethod(Slidex...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期氣相色譜-電子捕獲法測定血漿中的雷公藤甲素
...科,江蘇南京210002) 參考文獻:[1]ZHANGChong-pu, LChan-yu, MAPeng-cheng,etal.ActaPharmaceuticaSinica,1993,28(2):110-115 張崇璞,呂粲餘,馬鵬程,等.藥學學報,1993,28(2):110-115[2]LIHan-bao,WANGYu-xi,ZHAOZhong-kun,etal.JournalofChines...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文Sodiumchannelmutationsinepilepsyandotherneurologicaldisorders
...mplicatedbythedifficultyofcloningneuronalsodiumchannelcDNAs,whichareuniquelyunstableduringpropagationinbacterialcultures(unlikethemusclesodiumchannelcDNAsorthecalciumandpotassiumchannelcDNAs).FunctionalstudiesintheXenopusoocytesystemandintransfectedmammaliancellsdonotalwaysagree,andthereislittleexpe...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第8期BenefitofHepatitisCVirusCoreAntigenAssayinPredictionofTherapeuticResponsetoInterferonandRibavirinCombinationTherapy
...arcarcinoma(28,30).Successfulinterferon(IFN)therapyforHCVleadstopersistentlyundetectableserumvirallevelsandhistologicalimprovement(9,11)andimprovesthesurvivalofchronichepatitisCpatientsbypreventingliver-relateddeaths(36).Ameta-analysisstudyincludingdatafromrandomizedtrialsshowedthatretreatmentofnonr...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第1期Fatmeetsthecholinergicantiinflammatorypathway
...at-inducedactivationofthecholinergicantiinflammatorypathway(15).Therearemanyunknownsinthispathwaythatremaintobeaddressed.Oneunknowniswhetherdifferenttypesofdietaryfatvaryintheirabilitytoactivatethecholinergicantiinflammatorypathway.Itisalsopossiblethatdiet-inducedactivationofthecholinergicantiinflam...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第8期FrequentImportationofEnterovirus71fromSurroundingCountriesintotheLocalCommunityofYamagata,Japan,between1998and2003
...fromsurroundingcountrieshashadamajorepidemiologicalimpactonthelocalcommunityusedinourstudy.TEXTEnterovirus71(EV71)isamemberofthefamilyPicornaviridae,andbelongstothegenusEnterovirus(humanenterovirusA)(14).EV71isknowntobeacausativeagentofhand-foot-and-mouthdisease(HFMD),herpangina,asepticmeningitis,pa...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第12期EffectsofExerciseTrainingandDeconditioningonPlateletAggregationInducedbyAlternatingShearStressinMen
...rforGerontologicalResearch(J.-S.W.,Y.-S.L.,Y.-W.C.),ChangGungUniversity,Taoyuan,Taiwan;DepartmentofPharmacology(J.-C.C.),ChangGungUniversity,Taoyuan,Taiwan.CorrespondencetoJong-ShyanWang,GraduateInstituteofRehabilitationScience,ChangGungUniversity,259Wen-Hwa1stRoad,Kwei-Shan,Tao-Yuan,333,Taiwan.E-ma...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2005年第25卷第2期