小劑量茶鹼治療兒童哮喘臨牀療效觀察及免疫狀況影響
...5)。治療前後IFN-γ、IL-4、IFN-γ/IL-4;A組分別爲:(762±238)ng/L和(989±362)ng/L、(81.6±22.8)ng/L和(70.2±16.1)ng/L、9.6±4.1和14.4±11.2;B組分別爲:(783±261)ng/L和(957±374)ng/L、(80.9±23.5)ng/L和(67.3±19.3)ng/L、10.1±3.9和15.7±10.3,...
合作平臺;在線期刊;中華醫學研究雜誌;2004年第4卷第8期;臨牀醫學白細胞介素-1β和瘦素對人子宮內膜細胞粘附分子-1和金屬蛋白酶9的影響
...表達變化。結果分別經不同濃度的IL-1β和leptin干預後(0.1ng/ml的IL-1β除外),ICAM-1、MMP9mRNA較對照組相比表達增加,且隨濃度的升高,表達量呈上升趨勢。結論不同濃度的IL-1β和leptin可以通過促進子宮內膜中ICAM-1、MMP9mRNA的表達,進...
醫源資料庫;在線期刊;中華現代婦產科學雜誌;2010年第7卷第6期Urokinase-TypePlasminogenActivator,anEndogenousAntibiotic
...namurineinfectionmodel,uPAtreatmentalleviatedstaphylococcalsepsisbyinhibitingbacterialgrowth.TofurtherevaluatethechangesinuPAlevelsduringthecourseofstaphylococcalinfection,totaluPAandactiveuPAlevelswereanalyzedinplasmaandinkidneyhomogenates.ExpressionoftotaluPAwasconstant,butPAI-1levelsweredramatica...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第15期血管內皮生長因子的免疫學測定法
...抗體,以夾心法測定VEGF。結果:VEGF測定範圍爲0.02~200.00ng/ml,靈敏度可達0.02ng/ml,批內及批間變異均小於10%,回收率平均爲102.4%。其中人胃癌細胞MGC803、BGC823、乳癌MCF-7及肝癌BEL-7402分泌上清中VEGF的含量分別爲6.50、0.45、0.90及1....
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學HMG-CoAreductaseinhibitorsimvastatinmitigatesVEGF-inducedinside-outsignalingtoextracellularmatrixbypreventingRhoAactivation
...meA(HMG-CoA)reductaseinhibitorsexertmodulatoryeffectsonanumberofcellsignalingcascadesbypreventingthesynthesisofvariousisoprenoidsderivedfromthemevalonatepathway.Inthepresentstudy,wedescribeanovelpleiotropiceffectofHMG-CoAreductaseinhibitors,alsocommonlyknownasstatins,onvascularendothelialgrowthfacto...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第11期Cyclooxygenases,microsomalprostaglandinEsynthase-1,andcardiovascularfunction
...sylvania,USA.2DepartmentsofPhysiologyandBiochemistry,Queen’sUniversity,Kingston,Ontario,Canada.AbstractWeinvestigatedthemechanismsbywhichinhibitorsofprostaglandinG/Hsynthase-2(PGHS-2;knowncolloquiallyasCOX-2)increasetheincidenceofmyocardialinfarctionandstroke.Theseinhibitorsarebelievedtoexertbotht...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第5期ArteriosclerosisThrombosisandVascularBiology2003
...heleadershipofDrStevenLentz,wehaveinitiatedanewseriesoffocusedbriefreviews,titled“ATVBInFocus.“TheauthorsoftheseseriesareinvitedbyaGuestEditor,andthebriefreviews,ofcourse,undergotheusualpeerreviewprocess.Weandotherjournalsstrugglewithcriteriaforpublicationofgeneticassociationstudies.LastJuly,wei...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2003年第23卷第1期VascularEndothelialGrowthFactorIsInducedbytheInflammatoryCytokinesInterleukin-6andOncostatinMinHumanAdiposeTissueInVitroandinMurineAdip
...】Objectives-Itisbelievedthatadiposetissueactsasanendocrineorganbyproducinginflammatorymediatorsandtherebycontributestotheincreasedcardiovascularriskseeninobesity.Alinkbetweenadiposetissuemassandangiogenesishasbeensuggested.Vascularendothelialgrowthfactor(VEGF)seemstobeimplicatedinthisprocess.Membe...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第7期IL-1receptor–associatedkinaseMisacentralregulatorofosteoclastdifferentiationandactivation
...omthefusionofmacrophagesandtheyplayacentralroleinbonedevelopmentandremodelingviatheresorptionofbone.Therefore,osteoclastsareimportantmediatorsofbonelossthatleads,forexample,toosteoporosis.Interleukin(IL)-1receptor(IL-1R)–associatedkinaseM(IRAK-M)isonlyexpressedincellsofthemyeloidlineageanditinhibi...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第7期DietaryReferenceIntakesforfoodlabeling
...ericanSocietyforClinicalNutritionPublicInformationCommitteesymposiumfor2005titled“DietaryReferenceIntakes(DRIs)forFoodLabeling“servedasaplatformtoaddresstheuseofDRIsinfoodlabeling,achangethatcouldaffecttheprocessingoffoodsandsupplementsandthenutrientintakesofconsumers.Speakersfromscience,industr...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年83卷第5期