色譜法測定三羥乙基蘆丁的血藥濃度
...,用熒光檢測器測定。結果:血藥濃度標準曲線在1.25~40ng.mL-1間,r=0.9994;最低檢測限爲1 ng.mL-1;高、中、低3種濃度平均回收率爲91.52%~95.83%。日內和日間平均RSD小於4.3%和5.2%。結論:本法可爲羥乙基蘆丁的藥動學研究提供一...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文色譜法測定三羥乙基蘆丁的血藥濃度
...,用熒光檢測器測定。結果:血藥濃度標準曲線在1.25~40ng.mL-1間,r=0.9994;最低檢測限爲1 ng.mL-1;高、中、低3種濃度平均回收率爲91.52%~95.83%。日內和日間平均RSD小於4.3%和5.2%。結論:本法可爲羥乙基蘆丁的藥動學研究提供一...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例遺傳密碼:破譯曹操身世之謎?
...體是不會變化的。 由父子相傳的Y染色體相對穩定。然而,在傳承過程中,鏈條上的某些點會發生隨機突變,其中有一種突變類型叫做SNP。 SNP的突變是非常非常慢的,這個點上面產生了突變以後,要經過三千萬代纔會再...
行業資訊;臨牀快報;遺傳與基因組StatusofplasmafolateafterfolicacidfortificationofthefoodsupplyinpregnantAfricanAmericanwomenandtheinfluencesofdiet,smoking,andalcohol
...a.nih.gov.ABSTRACTBackground:AfricanAmericanwomenandsocioeconomicallychallengedwomenareatriskofcompromisedfolatestatusand,thus,offolate-relatedbirthdefects.DataarelimitedoncirculatingfolateconcentrationsinpregnantAfricanAmericanwomenafterfolicacidfortificationofthefoodsupplywasimplemented.Objective:...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年81卷第3期InvolvementofRhoARhoKinaseSignalinginVEGF-InducedEndothelialCellMigrationandAngiogenesisInVitro
...ctionMethodsResultsDiscussionReferences:Objective—Growthfactor-inducedangiogenesisinvolvesmigrationofendothelialcells(ECs)intoperivascularareasandrequiresactiveremodelingoftheendothelialF-actincytoskeleton.ThesmallGTPaseRhoApreviouslyhasbeenimplicatedinvascularendothelialgrowthfactor(VEGF)-induc...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2003年第23卷第2期11-HSD1inhibitionamelioratesmetabolicsyndromeandpreventsprogressionofatherosclerosisinmice
...se(HSD)type1convertsinactivecortisoneintoactivecortisolincells,therebyraisingtheeffectiveglucocorticoid(GC)toneaboveserumlevels.Wereportthatpharmacologicinhibitionof11-HSD1hasatherapeuticeffectinmousemodelsofmetabolicsyndrome.Administrationofaselective,potent11-HSD1inhibitorloweredbodyweight,insulin...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第4期ThematrixcomponentbiglycanisproinflammatoryandsignalsthroughToll-likereceptors4and2inmacrophages
...crophagesasanendogenousligandofTLR4andTLR2,whichmediateinnateimmunity,leadingtorapidactivationofp38,ERK,andNF-BandtherebystimulatingtheexpressionofTNF-andmacrophageinflammatoryprotein–2(MIP-2).Inagreement,thestimulatoryeffectsofbiglycanaresignificantlyreducedinTLR4-mutant(TLR4-M),TLR2–/–,andmy...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第8期高效液相色譜法測定三羥乙基蘆丁的血藥濃度
...,用熒光檢測器測定。結果:血藥濃度標準曲線在1.25~40ng.mL-1間,r=0.9994;最低檢測限爲1 ng.mL-1;高、中、低3種濃度平均回收率爲91.52%~95.83%。日內和日間平均RSD小於4.3%和5.2%。結論:本法可爲羥乙基蘆丁的藥動學研究提供一...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文LossofSOCS3inThelpercellsresultedinreducedimmuneresponsesandhyperproductionofinterleukin10andtransforminggrowthfactor–1
...yushuUniversity,Higashi-ku,Fukuoka812-8582,JapanSuppressorofcytokinesignaling(SOCS)3isamajornegativefeedbackregulatorofsignaltransducerandactivatoroftranscription(STAT)3-activatingcytokines.TransgenicmousestudiesindicatethathighlevelsofSOCS3inTcellsresultintype2Thelpercell(Th2)skewingandleadtohypers...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第4期海南島黎族3個支系DYS199、Y-27H39位點多態性的研究ˇ(基金項目)
...lymorphismanalysisforDYS199,Y-27H39ofthreeLipopulationsinHainanIslandLiDongna,ChenLu,ZhouZhenjian,etal.DepartmentofBiology,HainanMedicalCollege,Haikou571101.【Abstract】ObjectiveTostudythegeneticpolymorphismandpopulationdiversityoftwoY-DNAlociinLiethnicgroupsinHainanIsland.MethodsDYS19...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第14期;論著