Entryofparainfluenzavirusintocellsasatargetforinterruptingchildhoodrespiratorydisease
...inchildren—influenzaandmeasles—haveyieldedinparttovaccinationprogramsandantiviraltherapy,childrenarestillvirtuallyunaidedintheirbattleagainstthemajorcausesofcroupandbronchiolitis.RSVhasbeenextensivelystudied,andsomeeffectivestrategiesofprophylaxishavebeendeveloped(5),butfortheparainfluenzaviruse...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第7期抗乙型病毒性肝炎新藥——阿德福韋酯
...底物;(2)通過與HBVDNA多聚酶競爭而整合入病毒DNA鏈,導致DAN鏈的中止而最終抑制了HBVDNA的複製,使病毒DNA鏈延長終止。二磷酸阿德福韋對HBVDNA多聚酶的抑制常數爲0.1mmol/L,對人類DNA多聚酶α和γ的抑制作用較弱,其抑制常數分別...
醫源資料庫;在線期刊;中華實用醫藥雜誌;2006年第6卷第11期丹芍化纖膠囊對肝纖維化大鼠膠原降解的影響
...屬蛋白酶 EffectsofthetraditionalChinesemedicineprescription Dan-Shao-Hua-XiancapsuleondegradationofcollagenofCCl4-inducedhepaticfibrosisinratsWanChangwu,YangQin,XieRujia,etal.DepartmentofPathology,GuiyangMedicalCollege,Guiyang,Guizhou550004.【Abstract】ObjectiveToinvestig...
合作平臺;在線期刊;中華中西醫雜誌;2004年第5卷第17期;論著HBV所致終末期肝病患者肝組織膽管增生的研究
...hepatitisBvirusinducedend-stagechronicliverdisease CHENYao-kai,QIANYi-dan,WANGYu-ming. InstituteofInfectiousDiseases,SouthwestHospital,ThirdMilitaryMedicalUniversity,Chongqing400038,China 【Abstract】ObjectiveDuctularproliferationisfrequentlyobservedinthelivertissuesectionsofpatient...
醫源資料庫;在線期刊;中華現代內科學雜誌;2005年第2卷第11期HypercontractileFemaleHeartsExhibitIncreasedS-NitrosylationoftheL-TypeCa2+Channel1SubunitandReducedIschemia/ReperfusionInjury
...ecardiacSRCa2+releasechannel/ryanodinereceptor(RyR2)canbepoly-S-nitrosylatedandactivatedbyS-nitrosothiol(SNO)compoundsinvitro.7NOhasalsobeenreportedtomodulatetheactivityofSERCA2a8,9andtheL-typeCa2+channel,10eC12butthereisnodirectevidenceforS-nitrosylationoftheseCa2+transportersinsitu.Genderdifferenc...
醫源資料庫;在線期刊;循環研究雜誌;2006年第96卷第2期Ofmiceandmen:theironage
...tomas,diabetes,cardiomyopathy,arthritis,andendocrinopathies.Unlessrecognizedandtreated,thisdiseaseisfatal.Whilehereditaryhemochromatosishasbeenclinicallyrecognizedsince1889,itisonlyoverthe10pastyearsthatthegeneticbasisforthediseasehasbeenelucidated.Hereditaryhemochromatosisisnowrecognizedtobegenetic...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第8期阿昔洛韋治療基本型單皰病毒性角膜炎兩種用藥途徑的比較
...洛韋不和正常細胞的DNA聚合酶結合,不會影響正常細胞的DAN鹼基合成,因此毒性很低。阿昔洛韋的另一個特點是對深層組織有很好的滲透性,尤其容易進入受病毒感染的細胞內,因此無論對上皮型,基質型還是的內皮型單皰病毒...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第1期;論著廣東省水產品中香港海鷗型菌的污染調查與耐藥性檢測
...hLaribacterhongkongensisanddrugresistanceinGuangdongProvince. SONGMan-dan,YANJi-wen,ZHUHai-ming,etal. (GuangdongProvincialCenterforDiseaseControlandPrevention,Guangzhou510300,Guangdong,P.R.China) Abstract:ObjectiveTounderstandthecontaminationofaquaticproductbyLaribacterhongkonge...
醫源資料庫;在線期刊;中國熱帶醫學雜誌;2007年第7卷第8期PrevalenceofToxicShockSyndromeToxin1-ProducingStaphylococcusaureusandthePresenceofAntibodiestoThisSuperantigeninMenstruatingWomen
...ranus),withapproximately9%colonizedvaginally.Eighty-fivepercentofsubjectshadantibodytiters(1:32)toTSST-1,andthevastmajority(81%)ofteenagedsubjects(13to18years)hadalreadydevelopedantibodytiters.AmongcarriersoftoxigenicS.aureus,asignificantlylowerpercentageofblackwomenthanofwhiteorHispanicwomenwerefou...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期急性腦卒中早期肢體康復效果評價
...fectofextremityrehabilitationofcerebralapoplexypatientsXUXiu-hong,CUIBao-dan,SUNLi.DepartmentofNeurology,BethuneInternationalPeaceHospital,Shijiazhuang050082,China[Abstract]ObjectiveToresearchtheeffectofextremityrehabilitationnursingonfunctionalrecoveryandactivitiyofdailylivinginacutecereb...
醫源資料庫;在線期刊;中華現代護理學雜誌;2009年第6卷第4期