EvidenceofParvovirusReplicationinCerebralNeuronsofCats
...nstBayerne.V.,D-85586Poing,Germany2Received27November2002/Returnedformodification12January2003/Accepted26May2003 ABSTRACTTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesThecorrelationbetweenparvovirusinfectionsandlesionsinthecentralnervoussystemotherthancerebellarhypoplasiawas...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期農科院分子遺傳學試題(博士)2002年,2001年,1998年,1997年,1996年,1995年
...sion)18、弱化子(attenuator)19、基因家族(genefamily)20、CAT框(CATbox)二、填空題1、DNA聚合酶I有、、活性。2、在真核生物中存在3種RNA聚合酶,RNA聚合酶I負責的合成、RNA聚合酶II負責的合成、RNA聚合酶III負責的合成。3、細菌RNA...
醫源資料庫;醫源習題集;未分類試題Alleviationoffattyacidandhypoxia-reoxygenation-inducedproximaltubuledeenergizationbyADP/ATPcarrierinhibitionandglutamate
...zationinpermeabilizedtubulesmeasuredusingsafraninOuptakeandstudiedthemodificationofNEFA-induceddeenergizationbyinhibitorsoftheADP/ATPcarrierandglutamateusingbothnormoxictubulestreatedwithexogenousNEFAandtubulesdeenergizedduringhypoxia-reoxygenation(H/R).Amongthelong-chainNEFAthataccumulateduringH/Ro...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第5期ImpairmentoftheIntestinalBarrierbyEthanolInvolvesEntericMicrofloraandMastCellActivationinRodents
...Theoventemperaturewasprogrammedasfollows:100??Cfor1minute,then100??Cto200??Cat20??C/minute,holdtimeof5minutesat200??C,200??Cto220??Cat5??C/minuteand220??Cto280??Cat30??C/minutewithafinalholdtimeof4minutesat280??C.TheinjectorandGC-MSinterfacetemperaturesweresetat250??C.EImassspectraweregeneratedat70e...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第4期DietaryFat–InducedAlterationsinAtherosclerosisAreAbolishedbyACAT2-DeficiencyinApoB100Only,LDLr–/–Mice
...jectives—Theenzymeacyl-coenzymeA(CoA):cholesterolO-acyltransferase2(ACAT2)intheliversynthesizescholesterylesters(CE)fromcholesterolandfattyacyl-CoA,whichgetincorporatedintoapoB-containinglipoproteinsthataresecretedintothebloodstream.Dietaryfattyacidcompositioninfluencestheamountandfattyacidcom...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第6期Aminoacidsasmodulatorsofendothelium-derivednitricoxide
...kidneyasdifferentaminoacidswereaddedtotheperfusate.Theadditionof10-4or10-3Mcationicaminoacids(L-ornithine,L-lysine,orL-homoarginine)orneutralaminoacids(L-glutamine,L-leucine,orL-serine)totheperfusatedecreasedNOandincreasedrenalvascularresistance.Perfusionwithanionicaminoacids(L-glutamateorL-aspartat...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第8期新生兒缺氧缺血性腦病的治療進展
...胞內外OFR的清除有協同作用。幾種清除OFR的酶製劑(SOO、CAT)等尚缺少臨牀應用研究。近年來學術界對本病認識與治療有了不少深入的研究與進展,本文就其中幾項主要的治療做一綜合性介紹。1腦水腫的治療圍產兒腦的代謝極...
醫源資料庫;在線期刊;中華現代兒科學雜誌;2006年第3卷第5期優化GFP融合膜蛋白的表達與純化ZT(protocol)
OptimizationofmembraneproteinoverexpressionandpurificationusingGFPfusionsDavidDrew1,4,MirjamLerch1,4,EdmundKunji2,Dirk-JanSlotboom3Jan-WillemdeGier11DepartmentofBiochemistryandBiophysics,StockholmUniversity,SE-10691Stockholm,Sweden.2MRCDunnHumanNutritionUnit,HillsRoad,CB22XYCambridge,UnitedKingdom.3...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例淺談抗體領域的研究成果
...人源化單抗的需求也越來越迫切。1993年劍橋抗體技術(CAT)和巴斯夫生物研究公司(後爲Abbott收購)開始了第一個全人單抗Humira(抗體名Adalimumab)的研發,有賴於CAT的噬菌體展示技術(Phagedisplaytechnology),Humira於2002年作爲治...
醫藥經濟;生物技術;技術要聞EvidenceThattheCoactivatorCBP/p300IsImportantforPhenobarbital-InducedbutNotBasalExpressionoftheCYP2H1Gene
...hownthatonly50%ofphenobarbitalresponsivegenesareaffectedinCAR-nullmice,indicatingthatCARhasdiverseroles(Uedaetal.,2002).Studiesinthemousehaveshownthatinresponsetophenobarbital,CARistranslocatedtothenucleus,whereitformsaheterodimerwithretinoidXreceptorandactivatesdrugresponseelementsinthe5‘-flankin...
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