人血漿中奧美拉唑高效液相色譜測定法及其藥代動力學研究
...收率爲87.02%~98.07%,血漿中奧美拉唑的最低檢出濃度爲3ng.mL-1,線性範圍爲5~1800ng.mL-1。用本法測定了12名志願者隨機交叉口服單劑量40mg洛賽克膠囊和奧美拉唑腸溶片後血漿中奧美拉唑的濃度經時變化過程,並對其藥動學參數進...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文氣相色譜法測定頭孢匹胺中的殘留溶劑
...curvesofacetone,acetonitrileandN,Ndimethylformamidewerelinearwithintherangesof0.500~2.000μg,0.041~0.164μgand0.088~0.352μg(r=0.9997,0.9994and0.9999),respectively.Theaveragerecoveriesofacetone,acetonitrileandN,Ndimethylformamidewere101.1%,97.7%and100.4%,whiletheRSDforreplicationswere0.3...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文免疫分析法在獸藥殘留分析中的應用
...爲基礎進行酶聯免疫吸附試驗,檢測限分別爲肌肉組織1.0ng/g,肝臟2.8ng/g,脂肪1.5ng/g,表明這種方法的可行性很高。HorneE等[3]也報道採用IAC淨化兔肝臟中的噻苯咪唑(TBZ),以此爲基礎進行高效液相色譜,使得TBZ的檢測更加便利。由此可見,...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文衛當“出於上焦”
...://www.zysj.com.cn/lilunshuji/taisuzhenben/index.html“target=“_blank“title=“中醫書籍:黃帝黃帝內經太素》卷十二、《千金要方》卷二十第四、《外臺祕要·三焦病脈論》等均作“衛出上焦”,且《中藏經》的成書年代與《黃帝內經》的成...
中醫中藥;中醫臨牀;臨牀討論Modelofalbuminreabsorptionintheproximaltubule
...dedtofitmicropuncturedataontubulealbuminconcentrationsinrats.Formoderatechangesinfilteredload,therewasmuchgreatersensitivityofftoSNGFRthantothealbuminconcentrationofthefiltrate(C0).A50%increaseinSNGFRwaspredictedtocausefour-tofivefoldincreasesinalbuminexcretioninratsorhumans.ForlargeincreasesinC0,as...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第1期Controloftightjunctionalsealing:roleofepidermalgrowthfactor
...tophysiologicalrequirements,pathologicalconditions,andpharmacologicalchallenges.Thisisreflectedbyatransepithelialelectricalresistance(TER)rangingfromafewtenthtoseveralthousands·cm2,dependingonthedegreeofsealingofthetightjunction(TJ).Thepresentworkispartofanefforttounderstandthecausesandmechan...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第2期白細胞介素-1α對兔眼壓的影響及其眼內毒副作用的觀察
...每組5只兔.A~D組分別隨機一隻眼結膜下注射重組人IL-1α15ng(A組),前房內注射IL-1α1.5ng(B組)、15ng(C組)及40ng(D組);A~D組對側眼相應部位注射等體積的0.1%PBS。E組隨機一隻眼滴用噻嗎心安,對側眼滴用人工淚液。F和G組用藥方法和劑...
行業資訊;臨牀快報;藥理學MutationswithinSox2/SOX2areassociatedwithabnormalitiesinthehypothalamo-pituitary-gonadalaxisinmiceandhumans
...GeneticsUnit,InstituteofChildHealth,UniversityCollegeLondon,London,UnitedKingdom.3DivisionofDevelopmentalGenetics,MedicalResearchCouncilNationalInstituteforMedicalResearch,London,UnitedKingdom.4CancerResearchUK,SkinTumourLab,UniversityofLondon,London,UnitedKingdom.5CenterofPaediatricEndocrinology,De...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第9期Optimizationofaselfantigenforpresentationofmultipleepitopesincancerimmunity
1SwimAcrossAmericaLaboratoryofTumorImmunology,MemorialSloan-KetteringCancerCenter,NewYork,NewYork,USA.2WeillMedicalandGraduateSchoolsofCornellUniversity,NewYork,NewYork,USA.AbstractTcellsrecognizingselfantigensexpressedbycancercellsareprevalentintheimmunerepertoire.However,activationoftheseautoreact...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第5期利培酮和氟哌啶醇的臨牀對照研究
...0例)、氟哌啶醇組(33例)患者的基線SOD濃度[(794±126)ng/mgHb,(750±101)mg/mgHb]均明顯高於正常對照組[(483±110)ng/mgHb],而PRL濃度[(6±7)μs/L,(6±8)μg/L]均明顯低於正常對照組[(18±12)μg/L],差異均有統計學意...
行業資訊;臨牀快報;神經科