Roleof2-integrinsforhomingandneovascularizationcapacityofendothelialprogenitorcells
...re,wedemonstratethatexvivo–expandedEPCsaswellasmurinehematopoieticSca-1+/Lin–progenitorcellsexpress2-integrins,whichmediatetheadhesionofEPCstoendothelialcellmonolayersandtheirchemokine-inducedtransendothelialmigrationinvitro.Inamurinemodelofhindlimbischemia,Sca-1+/Lin–hematopoieticprogenitorce...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第1期Granulocyte/macrophagecolony-stimulatingfactorandaccessorycellsmodulateradioprotectionbypurifiedhematopoieticcells
...factor(GM-CSF)promotesthesurvival,proliferation,anddifferentiationofmyeloidlineagecellsandregulateschemotaxisandadhesion.However,miceinwhichthegenesencodingGM-CSF(Gmcsf)orthecommonsubunitoftheGM-CSFreceptor(c)areinactivateddisplaynormalsteady-statehematopoiesis.Here,weshowthathostGM-CSFsignalingstro...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第6期Osteopontinisahematopoieticstemcellnichecomponentthatnegativelyregulatesstemcellpoolsize
...achusettsGeneralHospital,HarvardMedicalSchool,Boston,MA021142HarvardStemCellInstitute,Cambridge,MA021383MedizinischePoliklinik,UniversityofBonn,53111Bonn,Germany4DepartmentofMedicine,UniversityofRochesterSchoolofMedicine,Rochester,NY146425DepartmentofCellBiologyandNeuroscience,RutgersUniversity,Pisc...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第11期Ahomingmechanismforbonemarrow–derivedprogenitorcellrecruitmenttotheneovasculature
...elltypes.However,themechanismsbywhichcirculatingprogenitorcellshometoremodelingtissuesremainunclear.Hereweshowthatintegrin4?1(VLA-4)promotesthehomingofcirculatingprogenitorcellstothe4?1ligandsVCAMandcellularfibronectin,whichareexpressedonactivelyremodelingneovasculature.Progenitorcells,whichexpressi...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第3期骨髓CD117+Lin-細胞移植對小鼠酒精性肝纖維化的影響*
【摘要】目的探討骨髓源性肝幹細胞(BMDLSC)移植對肝纖維化病變的影響。方法16只酒精性肝纖維化雌性小鼠隨機分爲移植組和對照組,移植組小鼠(n=8)接受同基因型雄性小鼠的骨髓CD117+Lin-細胞移植,對照組小鼠(n=8)接受等...
醫源資料庫;在線期刊;中華醫學研究雜誌;2009年第9卷第1期ImmunofluorescenceAssayforDetectionoftheNucleocapsidAntigenoftheSevereAcuteRespiratorySyndrome(SARS)-AssociatedCoronavirusinCellsDerivedfro
InstituteofMicrobiologyClinicalMedicineBiochemistryandMolecularBiology,CollegeofMedicine,NationalTaiwanUniversityDepartmentofPediatricsEmergencyMedicineInternalMedicine,NationalTaiwanUniversityHospitalCardinalTienCollegeofNursingNationalHealthResearchInstitute,Taipei,TaiwanABSTRACTAnantigendetection...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第5期2343例男科就診患者精子動態參數分析
...向性(STR)下降明顯,鞭打頻率(BCF)呈上升趨勢,而直線性(LIN)、擺動性(WOB)差異無顯著性;③與密度活力正常組比較:少精組除LIN、STR有所增加,MAD、BCF有所下降,差別有統計學意義外,其餘五項參數差別無統計學意義;弱精組除M...
醫源資料庫;在線期刊;現代泌尿外科雜誌;2008年第12卷第6期第七章 免疫細胞(一):造血幹細胞--第一節 造血幹細胞的特性
第七章 免疫細胞(一):造血幹細胞 在人和動物周圍血中,存在形態不同、功能各異的多種血細胞。它們是紅細胞、粒細胞、單核細胞、淋巴細胞及血小板。其生命亦各不同,如人紅細胞生命週期約120天,粒細胞約20~62...
醫源資料庫;醫源圖書館;教材類;醫學免疫學DetectionofSevereAcuteRespiratorySyndromeCoronavirusRNAinPlasmaduringtheCourseofInfection
...NAinplasmabeforeday11,togetherwiththerelativeconvenienceofcollectingandhandlingplasma,suggestthatplasmacanbeusedforearlydiagnosisofSARS.TEXTSevereacuterespiratorysyndrome(SARS)isanemerginginfectiousdiseasethatposesapotentialthreattothehealthofpeoplethroughouttheworld(10,16).Theetiologicalagentisanov...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期Interleukin-7isnecessarytomaintaintheBcellpotentialincommonlymphoidprogenitors
...A-3.Importantly,inducedoverexpressionofEBFissufficienttorestoretheBpotentialinthesecells.TheseresultsindicatethatIL-7directscommitmentofCLPsbymodulatingEBFexpression.Thisisthefirstexampleofacytokineinfluencinglymphoidlineagecommitmentinmultipotentprogenitorsandhighlightstherelevanceoftheexpressionof...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第6期