NovelGenomicLociInfluencingPlasmaHomocysteineLevels
...tedusingtheSIMWALK2softwareprogram.22Weconsideredmultipointlogarithmofodds(LOD)scores3.00asstatisticallysignificantevidenceoflinkage,2.00assuggestiveevidence,and1.30astentativeevidenceoflinkage.23ThesemultipointLODscorethresholdscorrespondtogenome-wideprobabilityvaluesof0.0001,0.001,and0.007respecti...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第7期AtherosclerosisSusceptibilityLociIdentifiedFromaStrainIntercrossofApolipoproteinE-DeficientMiceviaaHigh-DensityGenomeScan
...eEMalgorithmwasusedforintervalmappingwithinther/qtlsoftware,whichcalculatedLODscores(logoftheoddsratio)foreachphenotypeacrossthemousegenomeateverySNPpositionandin2-MbintervalsinregionswheremarkerSNPswerenotpresent.Lesionsizewasanalyzedbeforeandafterlog10transformation,whichnormalizesthedistributiona...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第3期Neuromedinß:astrongcandidategenelinkingeatingbehaviorsandsusceptibilitytoobesity
...31).ToidentifyregionofpromisinglinkageorQTL,weusedP0.0023orlogarithmofodds(LOD)1.75forbothlinkagemethods.Thislevelrepresents,onaverage,onefalsepositivelinkagesignalpergenomescanof400markers(32).Otherinterestingregions(suggestive)arereportedifP0.01orLOD1.17.Achi-squaredtestwasappliedtoevaluatewhether...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第6期腹腔鏡卵巢打孔術治療耐藥性多囊卵巢綜合徵15例分析
...米芬的PCOS患者應用腹腔鏡對卵巢進行單極電凝打孔術(LOD),術後出現排卵,並相應的獲得妊娠。1資料與方法1.1一般資料選擇2002年9月~2006年10月陽江市第三人民醫院不孕症門診治療的PCOS患者,在月經週期或黃體酮撤退性出血...
醫源資料庫;在線期刊;中華現代婦產科學雜誌;2009年第6卷第1期膽囊結石病致病基因的定位研究
...值(NPL)分別爲1.77(P=0.05)和1.92(P=0.04),參數分析優勢對數值(LOD)分別爲1.84和2.07。D3S1266位點的LOD值爲1.35。D11S902位點傳遞不平衡檢驗,P值爲0.0027。高發病年齡組D3S1266位點的LOD值由1.35上升到2.71,高甘油三酯組D9S1682位點的LOD值由2.07上...
行業資訊;臨牀快報;遺傳與基因組QuantitativeTraitLocusMappingofGenesThatRegulatePhospholipidTransferActivityinSM/JandNZB/BlNJInbredMice
...inmicefedchow(Pltpq1andPltpq2)werefoundonchromosomes3(34cM,logarithmofodds[LOD]3.5)and10(66cM,LOD4.1);twoadditionalQTLinmicefedatherogenicdiet(Pltpq3andPltpq4)werefoundonchromosomes9(56cM,LOD4.5)and15(34cM,LOD5.0);andoneQTL(Pltiq1)fortheinducibilityofPLTPactivitywasfoundonchromosome4(70cM,LOD3.7).Se...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第1期TheMexican-AmericanCoronaryArteryDiseaseFamilyStudy
...trongestevidenceoflinkagewasfoundonchromosome2atD2S2944(logarithmoftheodds[LOD]=3.08).Othersuggestivelinkageswerealsofoundonchromosome6atD6S1022toD6S2410(LOD=2.21)andchromosome13atD13S796toD13S895(LOD=1.34).Conclusions—TheseresultsshowthatthereisastronggeneticeffectonCIMTintheseMexicanAmericanCADf...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第3期藥物分析實驗數據處理
...B)/加入量A×100%回收率的RSD一般應爲2%以內。3.檢測限(LOD)是指分析方法能夠從背景信號中區分出藥物時,所需樣品中藥物的最低濃度,無需定量測定。LOD是一種限度檢驗效能指標,它既反映方法與儀器的靈敏度和噪音的大小...
藥品天地;專業藥學;實驗技術;色譜技術;色譜入門Sweettastepreferencesarepartlygeneticallydetermined:identificationofatraitlocusonchromosome
...tandsuggestivelinkageonchromosome2p22forsaturatedfatintake[logarithmofodds(LOD)2.62].Ouraimwastodeterminetheproportionofthegeneticfactorscontributingtothesweetnessperceptionofaqueoussolutionsandsweetfoodpreferencesinapopulationrandomlyselectedintermsofsweettastepreference-relatedphenotypes.Ifatraitw...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年86卷第1期EatingbehaviorintheOldOrderAmish:heritabilityanalysisandagenome-widelinkageanalysis
...videnceforlinkageofrestraintscoresto2chromosomalregions,nearmarkersD3S1304[LOD(logofodds)=2.5,P=0.0003]andD6S276(LOD=2.3,P=0.0006).WepreviouslyreportedthatD3S1304islinkedtoalocusinfluencingpercentagebodyfatinthissamepopulation(LOD=1.6),suggestingthatthisbehavioralphenotypemaybesecondarytoobesity.The...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年75卷第6期